Neuro enhancers or nootropics are used to treat various physiological and psychological deficiencies and disorders. In the contemporary scenario the administration of nootropics has increased because of growing stress oriented patients and altered life styles. In addition to their usage there has always been constant question on the mechanism of action of these respective drugs. The key factor in understanding the application of the nootropics is associated with the biochemical mechanism of the nervous system.
Neurotransmitters : The Messengers of mood
The nervous system is the main system which regulates control and coordination of the entire body. It regulates all physiological activities through feedback mechanisms linked to the brain and the spinal cord. The biochemistry related to nerve physiology and their respective signal conduction is a complex study in itself as it involves chemical messengers such as neurotransmitters. The mode of action of these neurotransmitters which are programmed by the nervous system upon release facilitate a respective effect related to the respective organ or physiological system.
Pharmacokinetics and Applications
Nootropics also known as smart drugs (commercial name) are categorised under nutraceuticals and supplement drugs which give accessory support to the physiology of the nervous system. Nootropics play a major role in the functionality and regulation of the brain signals. It enables the enhancement of memory facilitating the cognitive function. These drugs can promote and increase the oxygenation valuable to the brain in treating conditions such as apnoea to a certain extent. They enable the transfer of inter hemisphere information and also increase cortical and sub cortical activities.
Some of the common nootropics contain caffeine as a main ingredient and other L-theanine. On a comparative account pertaining to these two nootropics, L-theanine has less side effects as it does not hamper the normal sleep activity regulated by the brain which is prominent in caffeine users. The practice of appropriate nootropic is essential for good results. Each nootropic varies in its functionalities. Some nootropics such as modanifil work extensively in formation of the memory neural network.
L-theanine a good alternative to caffeine consumers have been much researched in the current scenario and it was effective in reducing anxiety to larger extent. In addition to this it also does not have aspects such as increased blood pressure and insomnia which most caffeine consumers experience. L-theanine is associated with the stimulation of alpha wave production from the brain which enhances relaxed attention in the subjects. L- theanine is abundantly found in green tea, black tea and mushrooms.
Caffeine also considered as the world’s largest consumed nootropic drug is a potent activator of the brain. In the current manufacturing and marketing scenario caffeine is incorporated in various forms such as energy drinks, medicines such as vasograin (used for migraine) and so on. This utilisation of the respective drug is based upon its natural availability in abundance and also its psychoactive and alert effects on the brain. The phenomenon of adenosine pathways A1 and A2 are bypassed initially however, the activity of the drug is believed to sustain irrespective of these pathways in residual conditions. On the other hand caffeine and also drugs like modanifil can cause sleep deprivation because of its cognitive action.
Side effects
The side effects pertaining nootropic drugs include nausea in case of excess consumption, headaches and irritability. In case of antidepressant nootropics such as Rhodoela rosea a natural eastern and European nootropic, mood changes and mild withdrawal symptoms have been reported. Other pharmaceutical preparations such as tyrosine and modanifil cause anxiety, insomnia and increased blood pressure.
Customised IV and MTM protocol for mood enhancement at RegenMed Care
At RegenMed Care we provide high quality customised IV therapy and MTM (Medication therapy management) protocols to revive energy and immunity for our patients which facilitates relaxation.