- It's replication occurs in the cytoplasm.
- Receptors for the virus replication are still unknown
- penetration of the cell is complex and involves many mechanisms.
- outer membrane is removed from the virus enters the cell
- membrane is further removed as it enters the cytoplasm and is shed to the core
- The virus expresses genes both before and after genome replication
- gene replication is self priming
- infected cells are then cleaved and reproduce
Pox Characteristics
- Largest and debatably most complex virus
- linear, double stranded DNA
- Wide range of hosts
- Divided into two subfamilies: Chordopoxvirinae and Entomopoxviridae
Cashin-Garbutt, A. (2012, October 04). Virus Uses. Retrieved January 30, 2017, from http://www.news-medical.net/health/Virus-Uses.aspx
Hughes, A. L., Irausquin, S., & Friedman, R. (2010, January). The Evolutionary Biology of Poxviruses. Retrieved January 30, 2017, from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2818276/
Poxviridae. (2009, January 09). Retrieved January 30, 2017, from http://virology-microbiology-b.blogspot.com/2009/01/poxviridae.html