Immune System project Zika virus

PATHOGEN BACKGROUND

1. TYPE OF PATHOGEN - Aedes Species Mosquito(Ae.aegypti and Ae.albopictus)

2. MICROSCOPIC PICTURE

Aedes Aegypti Mosquito

3. BACKGROUND INFORMATION

Zika Virus is discovered in 1947, actuallly found out this unknownvirus on rhesus monkeys in Zika forest of Uganda. But later in 1958, the studies shown that the Zika is primarily spread by the bites of the Aedes Species mosquito.

4. DEFENSE OF PATHOGEN- The pathogen have to bring down the Lymphocytes, B cell, T cells, and natural killer cells, all subtypes of white blood cells to bring down the host

TRANSMISSION

1.PORTAL OF ENTRY- The pathogen enters the body through by breaking the skin. Pathogen gets in the body and it moves through the body with the help of blood.

2. SPECIFIC MODE OF TRANSMISSION- Direct Contact: Zika can be transmitted through mosquito bites,Sex(person to person),From a pregnant woman to her fetus (Transplacental)and also blood transfusion.

3. PICTURE OF MODE OF TRANSMISSION-

4. INCUBATION PERIOD-

3-12 days, there is no specific treatment for Zika Virus. Symptoms will typically resolve within 4-7 days.

5.SPECIFIC TARGET OF THE BODY-

The virus can reach the nervous system from the bloodstream it can directly infects the never cells that can cause a disease called Guillain-Barre' Syndrome. And also it can cause another disease called microcephaly in fetus by damaging the normal development of the brain's structure.

6. PICTURE OF SPECIFIC TARGET OF THE BODY-

FIRST LINE OF DEFENSE

Body's first defense against the virus is the skin which makes hard for the pathogen to get into the body.Skin forms a waterproof mechanical barrier against the pathogen.

SECOND LINE OF DEFENSE

  • Second line of defense include inflammatory response which consists of mast cells, and histamine. And fever and also the pain.
  • Inflammation is caused by the mast cells.
  • Fever is another type of defense mechanism which can fight the Zika virus.

ACQUIRED IMMUNE SYSTEM

  • Cellular Immunity- T cells, which mature in the thymus, differentiate into cells that either participate in lymphocyte maturation, or kill virus-infected cells.
  • Humoral Immunity-Antibodies generally bind to virus particles in the blood and at mucosal surfaces, thereby blocking the spread of infection. In contrast, T cells recognize and kill infected cells.
  • Both humoral and cell mediated responses are essential for antiviral defense.

TREATMENT

  1. Treatment-There is no specific treatment/medicine for the Zika Virus .
  2. Vaccines- No vaccines or no medicines to treat it (but the studies are showing that they are working on the vaccines now).

CITATION

  • Wasserman, Emily. "Diagnostics Overlooked as 'first Line of Defense' for Zika Virus: WSJ." FierceBiotech. N.p., 02 Feb. 2016. Web. 02 Dec. 2016.
  • "Transmission & Risks." Centers for Disease Control and Prevention. Centers for Disease Control and Prevention, 24 Oct. 2016. Web. 02 Dec. 2016.
  • Editor in Chief, Harvard Health Publications, Harvard Health Publications Editor, Executive Editor Harvard Health Letter, Executive Editor, Harvard Women's Health Watch, Executive Editor, Harvard Men's Health Watch, and Executive Editor Harvard Heart Letter. "What You Need to Know about Zika Virus - Harvard Health Blog." Harvard Health Blog. N.p., 01 Feb. 2016. Web. 02 Dec. 2016.
Created By
Rony Mery Roy
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