When he was born he suffered with severe asthma. He would frequently have attacks and doctors could not cure it.
Despite that he still lived an active life, he sacrificed living a normal life, and the out come of it was that he became the president
No matter how bad things go keep your head up
Many years later on October 14, 1912, while campaigning in Milwaukee for his presidency, he was shot by a saloon keeper named John Flammang Schrank. The bullet got lodged in his chest and even with that he still gave a ninety minute speech while still bleeding. He showed the audience and said "It takes more than that to kill a bull moose." X-rays taken after the campaign event showed the bullet lodged against Roosevelt’s fourth right rib on an upward path to his heart. Fortunately, the projectile had been slowed by his dense overcoat, steel-reinforced eyeglass case and hefty speech squeezed into his inner right jacket pocket.
He still gave his speech, his motivation was that he had a goal to become the president. He nearly sacrificed his life just to give a speech. The outcome was that he won the Nobel Piece Prize.
No matter what happens keep going. If Teddy Roosevelt can give a 90 minute speech while bleeding out from a bullet wound, than we can pretty much do anything.