Gene Therapy to Prevent Blindness By: Khoi and Bryant

Our Topic, What it Does, How it Works, and How it Was Developed

Gene therapy to prevent blindness cures blindness and cures diseases using an injection or sometimes a droplet. It works by injecting a liquid into the rear of an eye where the disease occurs. Common diseases are proliferative diabetic retinopathy and age-related macular degeneration development. Most of the diseases for blindness occur in the rear part of the eye. They involve a substance called vascular endothelial growth factor, which stimulates the growth of blood vessels. Gene therapy for blindness has developed by using a lot of studies and investigations and past knowledge.

Proliferative diabetic retinopathy eye disease

Discoveries That Led to the Development of your Topic.

Most of the discoveries are discovered by a research team led by the University of Leeds. They found that the TSPAN12 gene is present in patients with a disease known as FEVR Familial Exudative Vitreoretinopathy. This affects the development of the eye which can cause blindness and other diseases. FEVR patients are usually blind or have poor vision. Although family members of the FEVR patients carry the faulty genes they aren’t blind or have any diseases from the person. Doctors are are trying to discover how to scan they eye and cure it before the person can become blind or have any diseases. A leader leading this research group said “This discovery will have an immediate impact on the treatment and counselling of some FEVR patients by allowing us to identify family members who carry the mutated gene before any retinal damage has occurred. This decreases their chances of going blind because if a patient is diagnosed early enough their sight can often be saved by surgical intervention."

How an eye looks in gene therapy for curing blindness

Impact on our Society Today

Gene therapy to prevent blindness has had a lot of impact on our society today. This is because it is curing a lot of people from diseases and blindness. It is also getting more advanced due to research groups and discoveries so more people will be cured easier and faster. So as time goes on, it will get better and better and easier to cure diseases that couldn’t be cured before before.

Blind Person

Our Prediction

Our prediction if it was more widespread is that it would have more advances, more people would be cured, and there would be more cures for other eye diseases. This is because if it was more widespread, more research groups would help and it would have better and faster advances. More people would be cured because there are more available places and people to cure these and get them done. There would also be more cures for other eye diseases because since there is so much people, they would have more time and chances to figure out more cures for diseases.

University of Leeds Research Group
Created By
Khoi and Bryant Pham and Huynh
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