GB Virus C is a flaviviridae. Viruses in the flavivirus family are all single-stranded RNA viruses. Production of a complementary RNA strand is not necessary for viruses in this family to produce protein. The genome of these viruses are on average 11,000 nucleotides long - they encode around 10 genes. The capsid of viruses in this family are icosahedral shaped and around the viral capsid a spherical shaped envelope is present.
Can GB Virus C Abate the HIV Virus???
"Because GBV-C is not associated with a disease, blood products are not screened for this virus and approximately 1 of 70 units of blood products in the United States contains GBV-C RNA"
Studies of the pathogenesis of GBV-C in HIV-infected patients yielded surprising results. Ten separate studies published or presented since 1998 found that GBV-C infection in HIV-positive people was associated with either a decrease in mortality or improved clinical outcomes.
Because both GBV-C and HIV replicate in lymphocytes, it is reasonable to speculate that viral interference between GBV-C and HIV might occur.
Data suggests that GBV-C replication induces cellular factors that might inhibit HIV.