Rheumatoid Arthritis By brody jerrick and odin ehrets

Rheumatoid Arthritis is an autoimmune disorder. This means that the white blood cells that attack regular diseases start attacking the body. In RA, the white blood cells attack the tissues in our joints and make the cartilage, ligaments, and the bone in the joint deteriorate. This in turn causes scarring, instability, and deformity in the joint. It is the most common autoimmune disease affecting 1% of people world wide. It may not seem much, but that's at least 70 million people throughout the world

Treatments include medication that causes the immune system to slow down. This makes it attack the joints less often. It also makes the person more susceptible to diseases so they'll be more sick than unaffected people for much longer.

X-Linked Dominant Genes


Black Square- Affected Male

White Square- Non-Affected Male

Black Circle- Affected Female

White Circle- Non-Affected Female

Joint during severe stages of RA

Rheumatoid Arthritis is an X-linked gene meaning men are more likely to get it. This is because, according to the American Society of Human Genetics, 135 simplex (1 person affected) and 30 multiplex (multiple people affected) families were studied. They concluded that proband gender and age of onset were both risks, but proband gender is much higher, leaving males a much higher chance of having RA or RA symptoms

RA is a very complex disease. Meaning that the genes just give a higher chance of symptoms occurring. The genes passed down just make your body more susceptible to getting Rheumatoid Arthritis, so you could have an entire family of people with RA and not have it, or you could be the first in your family to have it.

Healthy vs. Affected Joint


"Rheumatoid Arthritis Facts and Statistics." RheumatoidArthritis.org. N.p., n.d. Web. 12 Mar. 2017.

X-linked Pedigree Chart. Digital image. GAMSAT Section 3: Studying Pedigree Charts. N.p., n.d. Web. 12 Mar. 2017.

Rheumatoid Arthritis. Digital image. Rheumatoid Arthritis. N.p., n.d. Web. 12 Mar. 2017.

Rheumatoid Arthritis. Digital image. Rheumatoid Arthritis (RA). N.p., n.d. Web. 12 Mar. 2017.

Lynn, A. H., C. K. Kwoh, C. M. Venglish, C. E. Aston, and A. Chakravarti. "Genetic Epidemiology of Rheumatoid Arthritis." American Journal of Human Genetics. U.S. National Library of Medicine, July 1995. Web. 12 Mar. 2017.

Slomski, Genevieve T. "Rheumatoid Arthritis." The Gale Encyclopedia of Genetic Disorders, edited by Brigham Narins, 2nd ed., vol. 2, Gale, 2005, pp. 1116-1121. Gale Virtual Reference Library. Accessed 12 Mar. 2017.

Rheumatoid Arthritis. Digital image. Rheumatoid Arthritis. N.p., n.d. Web. 12 Mar. 2017.

Made with Adobe Slate

Make your words and images move.

Get Slate

Report Abuse

If you feel that this video content violates the Adobe Terms of Use, you may report this content by filling out this quick form.

To report a Copyright Violation, please follow Section 17 in the Terms of Use.