Gene Therapy to Improve Muscle Control in Parkinson's Patients By christine dziura and jayden le

Parkinson’s disease is a disorder of the nervous system that affects movement. This disease usually causes stiffness and shaking movement. People who have Parkinson’s disease are called Parkinson’s patients. Although it can’t be cured, gene therapy can help improve muscle control by replacing missing/defective brain cells with healthy ones. Gene therapy was first invented on September 14, 1990, but it wasn’t used in Parkinson’s patients until the year 2007.

The idea of replacing defective dna with good dna was first introduced during the 1970s. Later, a system was designed that could insert genes into mammalian chromosomes. This invention was first used on a four year old patient who suffered from ADA-SCID, an immune system deficiency. This treatment was successful and people began researching more about gene therapy. They were able to insert genes into the brain and they decided to use gene therapy to help people with inherited diseases. Gene therapy was first used in Parkinson’s patients during the year 2007 and they still continue to use gene therapy to help improve muscle control.

Symptoms of Parkinson's Disease

Gene therapy made little impact with Parkinson's patients as they are still experimenting on it. In fact, gene therapy had also made little impact with other inherited diseases. Many patients who have received gene therapy are often left with severe side effects, giving gene therapy a bad reputation. Because there are more failures with gene therapy than success, gene therapy is never the go-to choice when it comes to diseases. Good thing is that researchers are able to treat Parkinson's patients without having side affects but they still have a long way to go before they can have complete control in their muscles.

Evidence that suggests that gene therapy can ease Parkinson's symptoms with no side effects.

If this topic became more widespread, gene therapy might have a higher chance of succeeding for many reasons. For example, if this topic is more widespread, than that means that there will be more people researching on it. Another reason for this is that there will be more volunteers who would want the treatment, even if it goes wrong. The downside of this is that there would be more failures but that is normal with all experiments. In conclusion, gene therapy might have a higher chance of succeeding but it would require a more failures.

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J Le

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