Wednesday, August 14, 2019
380 S. University Avenue, Hill Pavilion and Lobby, Philadelphia, PA 19104
8:30 a.m.-5:00 p.m.
In 1994, Dr. Ralph Brinster at Penn Vet published his landmark discovery of Spermatogonial Stem Cell (SSC) transplantation, thereby transforming the fields of reproductive biology and regenerative medicine. To mark the 25th anniversary of SSC transplantation, we have planned an one-day symposium for scientific exchange among students, faculty, and researchers. The theme will be “IRM/Penn Vet: Frontiers of Germ Cell Research”. The symposium will include talks from Penn faculty members that highlight collaborative research projects and feature national and international speakers discussing emerging areas of germ cell research. The talks will fall within the global one health initiative: “One health, many species”, featuring research in mice, domestic large animals, primates, and humans. The keynote speaker will be Dr. David Page, Director of Whitehead Institute and a pioneer in genomics of sex chromosomes. The symposium is free to all attendees and open to all researchers inside and outside of University of Pennsylvania. Overall the symposium will provide a unique platform for integrating knowledge and exploring new frontiers in the field.
MONDAY, JULY 15, 2019
REGISTRATION IS NOW CLOSED
The symposium is sponsored by Penn's Institute of Regenerative Medicine (IRM), Penn's School of Veterinary Medicine, Center for Research on Reproduction and Women’s Health, and the Penn Center for Study of Epigenetics in Reproduction.
8:00 - 8:45 Registration & Breakfast
8:45 - 9:00 Welcome: Jeremy Wang, MD/PhD
Opening Remarks: Dean Andrew Hoffman, DVM, DSc
9:00 - 9:30 Opening Address (Introduction by Dean Hoffman)
Ralph Brinster, VMD, PhD
Spermatogonial stem cell overview
Session 1: Foundation and Applications of SSC Transplantation
Chair: Jeremy Wang
9:30 - 10:00 Ina Dobrinski, DVM, PhD
Germ cell transplantation and beyond: applications in large animal models
10:00 - 10:30 Jon Oatley, PhD
Surrogate sires: germline transplantation to enhance livestock production
10:30 - 10:45 Coffee Break
10:45 - 11:15 Jurrien Dean, MD
Spermatogonial stem cells, piRNA and monospermic fertilization
11:15 - 11:45 Takashi Shinohara, PhD
Aging of spermatogonial stem cells by Jnk-mediated glycolysis activation: Long live the spermatogonial stem cells!
11:45 - 12:15 Sandra Ryeom, PhD
Fertility preservation for pre-pubertal boys after chemotherapy-induced infertility
12:15 - 1:15 Lunch in H132 and Hill Pavilion Lobby
Session 2: Emerging and Translational Research
Chair: Marisa Bartolomei, PhD
1:15 - 1:45 Kotaro Sasaki, MD/PhD
In vitro gametogenesis in humans
1:45 - 2:15 Sue Hammoud, PhD
The power of one: novel perspectives of single-cell technologies in gametogenesis
2:15 - 2:45 Monica Mainigi, MD
Assisted reproductive technologies and adverse perinatal outcomes: The what, why & HOW?
2:45 - 3:15 Kyle Orwig, PhD
Stem cell therapies for male infertility
3:15 - 3:30 Coffee Break
3:30 - 3:45 Introduction of Dr. Page by Christos Coutifaris, MD.
3:45 - 4:45 Keynote Lecture
David Page, MD
Mammalian germ cells are determined after PGC colonization of the genital ridge
4:45 - 5:00 Closing Remarks: Ken Zaret, PhD
5:00 - 6:00 Reception
Opening Address: Dr. Ralph Brinster, Richard King Mellon Professor of Reproductive Physiology, National Medal of Science Recipient 2010
Keynote Speaker: Dr. David Page, Whitehead Institute, HHMI, and M.I.T.
Dr. Jurrien Dean, National Institute of Diabetes and Digestive and Kidney Diseases (NIH/NIDDK)
Dr. Ina Dobrinski, University of Calgary
Dr. Sue Hammoud, University of Michigan
Dr. Monica Mainigi, University of Pennsylvania Perelman School of Medicine
Dr. Jon Oatley, Washington State University
Dr. Kyle Orwig, University of Pittsburgh
Dr. Sandra Ryeom, University of Pennsylvania Perelman School of Medicine
Dr. Kotaro Sasaki, University of Pennsylvania School of Veterinary Medicine
Dr. Takashi Shinohara, Kyoto University
Organizing Committee: Marisa Bartolomei, Christos Coutifaris, Kotaro Sasaki, Jeremy Wang
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For additional information contact: Shivani Berry (email@example.com)