Watson & Crick
- Watson and Crick are most popularly known for their double he lix model of DNA, not for discovering DNA.
- The pair won the Noble Prize in 1962, but there colleague Rosalind Franklin died before they were awarded it, so she is not given as much credit
- Their 3 dimensional model changed the way people saw DNA and opened up new pathways of research.
- Erwin Chargaff made 2 rules essential to future research in DNA
- His first rule said that there is the same amount of guanine (G) as cytosine (C), and the same amount of adenine (A) as thymine (T)
- His second rule said that the DNA of different species differs in its proportions of guanine to adenine
How Do DNA Base Pairs Bind?
- As said in Chargaff's first law, only adenine and thymine can bind, and guanine and cytosine can bind
- The bases bind together from hydrogen bonds formed between them
- Each half of the helix is complementary to the other half, allowing only them to bond