Cystic Fibrosis By Kevin Coran

Cystic fibrosis is a disease where the mucus that is developed is more thick and sticky than normal.

Difference of lungs in regular and cf lungs

Cystic fibrosis is caused by the cystic fibrosis trans membrane conductance regulator gene. This gene is responsible for making the protein with the same name.

Cystic fibrosis was discovered in 1938 by Dorothy Anderson.

30,000 people in the United states are affected by cystic fibrosis, and approximately 70,000 worldwide. One in every 3,500 Caucasians has cystic fibrosis. The incidence rate in all other ethnic groups is much lower.

The main way people are diagnosed is by testing the levels of salt in sweat. In infants the main way to diagnose is to check the levels of immunoreactive trypsinogen.

There is no absolute cure for cystic fibrosis there are many treatments that attempt to reduce the risk of infection. Therapies are made to reduce mucus levels. Because there is no cure the average life expectancy is around 37 years.

To get cystic fibrosis you need to receive a mutated gene from both parents because it is a recessive trait.

Current research of gene therapy is replacing the mutated genes. There is also pharmaceutical therapy that can be used.

Works Cited

Giddings, Sharon. Cystic Fibrosis. New York, Chelsea House, 2009. Genes and Disease.

Mayo Clinic Staff. “Cystic Fibrosis.” Mayo Clinic, 13 Oct. 2016, Accessed 5 Feb. 2017.

Trivedi, Bijal P. “Doorway to a Cure for Cystic Fibrosis.” Discover Magazine, 30 July 2013. Accessed 5 Feb. 2017.

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