Toward the end of this life, Newton lived at Cranbury Park, near Winchester, England, with his niece, Catherine (Barton) Conduitt, and her husband, John Conduitt. By this time, Newton had become one of the most famous men in Europe. His scientific discoveries were unchallenged. He also had become wealthy, investing his sizable income wisely and bestowing sizable gifts to charity. Despite his fame, Newton's life was far from perfect: He never married or made many friends, and in his later years, a combination of pride, insecurity and side trips on peculiar scientific inquiries led even some of his few friends to worry about his mental stability.
By the time he reached 80 years of age, Newton was experiencing digestion problems, and had to drastically change his diet and mobility. Then, in March 1727, Newton experienced severe pain in his abdomen and blacked out, never to regain consciousness. He died the next day, on March 31, 1727, at the age of 84.