Schizophrenia By: Sarbelia, Lauren, OMaima, Savanna, Brianna

What Is It: Severe, chronic mental disorder. It is hard for a person to figure out what is real or fake.
Symptoms: delusions, hallucinations, and disordered thinking/speech/behavior.
Caused By (theories): genetics, chemical imbalance (dopamine, glutamate, & serotonin)
Not Caused By: poor parenting & bad childhood memories.
Risk: Having a schizophrenic twin (chances are that the other will have a 41/65 risk),old aged fathers during conception (increases risk), genetics (creates 9 times greater risk of having schizophrenia), having a 1st degree relative with the illness (creates a higher 10% chance of having the schizophrenia)
Treatment: anti - psychotic medicine (such as pills and injections) & cognitive therapy.
Relation to other illnesses: closely linked to bipolar disorder and autism. The enlargement of the ventricles is similar to autism & bipolar disorder. Experiments have shown links between all three illnesses.
Twin Schizophrenia Experiment: embryonic fetal exposure to nutrients (vitamin B - maternally derived) effects fetal development. (vitamin B) effects fetal development (dramatic epigenetic phenomenon). 800,000 samples were taken and it showed 108,000 specific traits, which is relative with autism
Twin Experiment Continued: DNA methylation (the gene that controls gene expressions) profiles are quite similar at birth over time; markers change from chance/environments.
Key Facts: 1/100 people have schizophrenia, hard to diagnose in teens,typically nonviolent people, it affects males more than females.
Effects: low iq (noticeable at an early age), less brain activity, makes it difficult to socialize, & keep a job. Also the loss of brain matter, which is a long process & completed by mid 20's, and misses milestones.

Works Cited:

Alonzi, Adam. The Epigenetics of Schizophrenia. WhatisEpigenetics.com, 8 December 2014, www.whatisepigenetics.com/the-epigenetics-of-schizophrenia/. Accessed 8 March 2017.

Meade-Kelly, Veronica. Researchers Shed New Light on Schizophrenia. Harvard Gazette, 21 July 2014, www.news.harvard.edu/gazette/story/2014/07/researchers-shed-new-light-on-schizophrenia/. Accessed 8 March 2017.

Newman, Tim. Bipolar, Austism, and Schizophrenia Might Share Genetic Origin. MNT, 6 May 2016, www.medicalnewstoday.com/articles/309963.php. Accessed 8 March 2017.

Nishioka, Misaki. DNA Methylation in Schizophrenia: Progress and Challenges of Epigenetic Studies. BioMed Central, 13 December 2012, www.genomemedicine.biomedcentral.com- /articles/10.1186/gm397. Accessed 8 March 2017.

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