Even though the practice of immunizations and remedies have been around for hundreds of years, Edward Jenner created one of the first vaccines. He treated a thirteen-year-old with smallpox by inserting pis from a cowpox bump into the patient. Edward Jenner discovered that milk maids with cowpox would develop and immunity to smallpox. In 1798, he published his findings and helped the history of vaccines. But, the Europeans had an immunity when they came to North America. The Native Americans that came in contact with the Native Americans were lacking the immunity because these diseases had never been in the Western Hemisphere before.
When the Europeans came to North America, they brought many things such as new technology and diseases. Over twenty-million people died, which was nearly 95% of the population in the Americas. Many of the people who were living in the Americas became ill. The Europeans had an immunity, so they benefitted the situation. Immediately after the Europeans step foot in North America, the history of diseases forever changed around that moment.