In the Watchmen comic, a major reoccurring theme is whether it is better to be isolated from the world or to have strong bonds with other humans.
One of the main characters, Dr. Manhattan, has extraordinary, God-like powers including the ability to see/be in the future and past at the same "time." This power causes him to be emotionally isolated from other people and events since he already knows what is going to happen. He exists in multiple points in time, so he cannot alter the future since he is experiencing the future while in the present. This leads to further isolation as others do not understand why he will not help out often.
By the end, however, Dr. Manhattan finally sees the value in human life. This goes even to the point of him suggesting that he will go to a different galaxy and create human life there. Does this support the notion of isolation since he leaves Earth or does this support the notion of connection since he is so fascinated by humans now that he is going to create more human life? I say it supports connection because he is going out and spreading life as opposed to simply abandoning humanity.
In part three there is the above discussion between a boy and a news vendor. The news vendor basically says that everyone is alone and can only rely on themselves. This supports the notion of isolation present throughout Watchmen.
However, the news vendor quickly changes his mind after learning that the Russians are invading Afghanistan as it makes Nuclear War much more likely. Over the span of a few pages his isolationist philosophy is discarded in favor of a new philosophy where people share and look out for one another. This makes this encounter between the boy and the news vendor one that now supports the notion of human connection as opposed to supporting isolation.