Cleopatra VII she was about 17 years old and had no son and had to marry her younger brother. Cleopatra tried to keep Egypt's independence during a time of Roman domination by allying herself romantically with Roman commanders Julius Caesar and Mark Anthony. She had a son, Caesarion, supposed to be fathered by Julius Caesar. When she died, Egypt's rule passed into the hands of Rome.
Cleopatra I was married to Ptolemy V was part of a peace negotiation with her father. The Egyptians called her "the Syrian." Cleopatra I was appointed regent for her son, and ruled as sole ruler until her son came of age. Her name preceded that of her son in many of the documents between her husband's death and 176 BCE, apparently the year that she died.
Nefertiti the claim that Nefertiti ruled after the death of her husband, Akhenaton. Based on the theory that she assumed the name Smenkhkare after his death. Even though she did not rule, during her husband's reign she was accorded more honor than usual for a Great Wife, and is sometimes depicted as a co-equal officiant at ceremonies.
Hatshepsut, widow of Thutmosis II, she ruled first as regent for his minor stepson and heir, and then as Pharaoh. She wore a fake beard and with the objects that a Pharaoh is usually depicted with, and in male attire, after a few years of ruling in female form. She disappears suddenly from history, and her stepson may have ordered the destruction of images of Hatshepsut and mentions of her rule.
Ahmose-Nefertari wife and sister of the dynasty's founder Ahmose I, and mother of the second king, Amenhotep I, Ahmose-Nefertari served as co-regent during her son's minority and co-regent with her grandson Thuthmosis I during his minority. "She was the first to hold the title of God's wife of Amun."
Sobeknefru- She was the daughter of Amenemhet III and half-sister of Amenemhet IV and also his wife. She claimed to have been co-regent with her father. The dynasty ends with her reign, as she apparently had no son. She only ruled for a few years. Titles found with her image include Female Horus, King of Upper and Lower Egypt, Daughter of Re.