The Nucleus
- The Nucleus is made up of a nuclear membrane (of phospholipids), a nucleolus, and chromosomes. It has a spherical-elliptical shape.
- It's job is to carry genetic info (DNA) as well as regulate the general function of the cell (reproduction, growth, etc.)
- All Eukaryotes have one, but prokaryotes don't. Nuclei are prolific in eukaryotes
- Diseases may include Emery-Dreifuss disease (causes movement restrictions), and others such as muscular dystrophy.
- Fun fact: Every human cell has around 6ft worth of DNA all tightly compacted in the nucleus!
Ribosomes
- Ribosomes are tiny globular/egg-shaped organelles made up of 2 protein subunits as well as rRNA.
- Their main function is protein synthesis by using mRNA derived from DNA in the nucleus.
- They are found in all types of organisms (both prokaryotes and eukaryotes) and they are abundant in all organisms.
- Diseases may include Diamond-Blackfan anemia (when bone marrow doesn't function properly), as well as dyskeratosis congenita, and treacher collins syndrome.
- Fun fact: Ribosomes aren't surrounded by a membrane like other organelles!
Rough Endoplasmic Reticulum
- The rough ER is a series of flattened sacs of membrane connected to the nucleus with ribosomes bound to it.
- They create membranes and secretory proteins which will be transported to the Golgi body or the smooth ER and then exported out of the cell.
- Both plants and animal cells have a rough ER, but they're mainly prolific in pancreatic cells.
- Diseases may include Parkinson's disease, which affects movement and you may experience super shaky hands.
- Fun fact: Hemoglobin is produced here by the ribosomes attached to the rough ER!
Smooth Endoplasmic Reticulum
- The smooth ER is connected to the rough ER and is tubular shaped.
- They create lipids and carbohydrates and also act as the transitional area for product from the rough ER. It also plays a role in detoxification.
- Both plants and animal cells have a smooth ER, but they're mainly prolific in liver cells.
- Diseases may include Type 2 diabetes (high blood sugar concentration in the bloodstream), as well as atherosclerosis.
- Fun fact: It's called the smooth ER because it doesn't have ribosomes bounded to it.
The Golgi Apparatus
- The Golgi apparatus is a stack of flattened sacs in a semi-circular shape.
- The Golgi apparatus modifies products of the ER (both) and then transports them off to the rest of the cell.
- Both plants and animals have Golgi apparatuses, but they're mainly prolific in pancreatic cells.
- A Golgi apparatus disease may include Parkinson's disease, which affects movement and causes shaky hands (as mentioned in the rough ER).
- Fun fact: Molecules already modified by the Golgi apparatus can be modified again by the same Golgi apparatus!
Mitochondria
- Mitochondria are rod-shaped organelles that are double membrane-bound (one has a phospholipid bilayer), they have their own DNA and ribosomes.
- Mitochondria synthesize energy for the cell by making ATP from cellular respiration.
- Both plants and animal cells have mitochondria, but they're mainly prolific in fat cells.
- Diseases for mitochondria may include multiple mitochondrial dysfunction syndrome, where multiple stage of impaired energy production occurs, which may lead to weak muscle tones and severe brain dysfunction.
- Fun fact: They reproduce separately from the rest of the cell and contain their own DNA!
Chloroplast
- Chloroplasts are ovular organelles with membrane bound sacs inside of it. Chloroplasts also contain chlorophyll, which are green pigments for photosynthesis.
- Chloroplasts are like the mitochondria of plant cells, they produce energy for the cell, but through photosynthesis instead of cellular respiration.
- Chloroplasts are found only in plant cells, and are prolific in the leaf cells.
- A chloroplast disease may include a phenotype mutation which can result in the whitening of plants.
- Fun fact: Like mitochondria, chloroplasts reproduce separately from the cell and also contain their own DNA.
Flagellum
- Flagella are whip-like structures protruding from the cell and connected to the cell membrane.
- Flagella are mainly only used for cell movement.
- Both Prokaryotes and Eukaryotes have flagella, but they're mainly prolific in sperm cells.
- Diseases associated with Flagella include one called Ciliary dyskinesia which affect the respiratory tract and cause breathing problems.
- Fun fact: The flagella found in eukaryotic cells are way different from those of prokaryotes. Eukaryotic flagella have the cell membrane surrounding it as well, while prokaryotic flagella do not.
Cillia
- Cillia are hair-like structures protruding from the cell.
- Like flagella, cillia mainly only function in cell movement.
- Only animal cells contain cillia, and they are mainly prolific in the respiratory tract and egg cells.
- Diseases associated with cillia can the same as the disease associated with flagella like ciliary dyskinesia, which affects the respiratory tract and causes breathing problems.
- Fun fact: Although they are mainly used for movement, in the respiratory tract, cillia function in noses by taking out dust particles in the air we breathe.
Lysosome
- Lysosomes are spherical-like membrane bound sacs containing digestive enzymes.
- Their main function is in disposal of wastes, digestion of nutrients (when with a food vacuole), and cell death.
- Lysosomes are only found in eukaryotes and are prolific in digestive cells like the liver, pancreas, etc.
- Diseases for lysosomes may include Pompe's disease (which weakens muscles, enlarges the liver, and causes heart defects), Hurler syndrome, and Tay-Sachs disease.
- Fun fact: Since lysosomes function in cell death as well, they are nicknamed the "suicidal sacs."
Food Vacuole
- Food vacuoles are globular, membrane bound sacs, resembling larger vesicles.
- Food vacuoles function in food storage and digestion (when working with a lysosome).
- Only eukaryotes contain food vacuoles, and they are mainly prolific in single-celled organisms like amoebas.
- Diseases may include Danons disease which causes the weakening of heart muscles and skeletal muscles.
- Fun fact: Animal cells contain many small vacuoles while a plant cell really only has one large vacuole.
Central Vacuole
- The Central vacuole is a gigantic membrane bound sac in the center of a plant cell.
- The central vacuole stores nutrients in the cell, stores water, controls cell turgor/pressure, and stimulates cell growth.
- Only plants have a central vacuole, and so they are prolific only in plants.
- Diseases associated with the central vacuole includes a disease known as "central vacuole disease state." In this state, the whole organelle shuts down, which allows toxins into the cell, killing it.
- Fun fact: Sometimes a central vacuole can contract in order to pump excess water out of the plant cell.
Sources
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Ozcan, Lale, and Ira Tabas. "Role of Endoplasmic Reticulum Stress in Metabolic Disease and Other Disorders." Annual Review of Medicine. U.S. National Library of Medicine, 2012. Web. 26 Nov. 2016.
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https://prezi.com/hy8hg1-v91ix/central-vacuole/