Heme iron supplement tablets first appeared in the seventies in Scandinavia. They are still in large use because of excellent tolerance and good efficacy.
Today the third generation of heme iron supplement tablets is rapidly gaining popularity worldwide.
Natural hemoglobin contains heme iron, which is the most efficient and well-tolerated source of palatable iron for man.
The only other kind, non-heme iron, is found in plants and chemical/synthetic forms of supplements.
Heme iron and its good properties were known in the medical community. After the first products appeared, there were clinical studies confirming absorption and tolerance. Heme iron is easily absorbed as a whole structure with high bioavailability.
Non-heme iron must be dissolved before uptake. Because of low absorption reactive free iron ions remain in the gut causing disturbancies/side-effects.
A number of heme-iron based tablet food supplements have been introduced since the 1970-ies in Scandinavia.
Despite major general use no cases of serious side-effects or of poisoning have been reported
This form of iron supplementation has been unique to Scandinavia, since nowhere else is the technology and know-how needed present.
For chronics, when iron deficiency is linked to the disease, the situation can be critical. Sooner or later almost everyone develops side-effects that eventually terminate the vital therapy.
The traditional alternative remaining has been intravenous supplementation, which is costly, painful and inconvenient. It also brings oxidative stress to the organism
Today, more and more doctors and health authorities around the world are realising that natural heme iron therapy is safe, economical, well-tolerated and efficient.